Article
Effect of hydrogen peroxide production and the Fenton reaction on membrane composition of Streptococcus pneumoniae.
Biochimica et biophysica acta - 1 Mar 2007
Pesakhov Stella, Benisty Rachel, Sikron Noga, Cohen Zvi, Gomelsky Pavel, Khozin-Goldberg Inna, Dagan Ron, Porat Nurith
Abstract excerpt
As part of its aerobic metabolism, Streptococcus pneumoniae generates high levels of H(2)O(2) by pyruvate oxidase (SpxB), which can be further reduced to yield the damaging hydroxyl radicals via the Fenton reaction. A universal conserved adaptation response observed among bacteria is the adjustment of the membrane fatty acids to various growth conditions. The aim of the present study was to reveal the effect of...
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