Article
Peroxiredoxin 5 modulates immune response in Drosophila.
Biochimica et biophysica acta - 1 Nov 2010
Radyuk Svetlana N, Michalak Katarzyna, Klichko Vladimir I, Benes Judith, Orr William C
Abstract excerpt
BACKGROUND: Peroxiredoxins are redox-sensing enzymes with multiple cellular functions. Previously, we reported on the potent antioxidant function of Drosophila peroxiredoxin 5 (dPrx5). Studies with mammalian and human cells suggest that peroxiredoxins can modulate immune-related signaling. METHODS: Survivorship studies and bacteriological analysis were used to determine resistance of flies to fungal and bacterial...
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