Article
Parkin-mediated responses against infection and wound involve TSPO-VDAC complex in Drosophila.
Biochemical and biophysical research communications - 1 Jan 2000
Cho Jae Ho, Park Jeong Hyang, Chung Chang Geon, Shim Hyun-Jung, Jeon Keun Hye, Yu Seong-Woon, Lee Sung Bae
Abstract excerpt
Parkin, an E3 ubuquitin ligase associated with Parkinson's disease (PD), has recently been implicated in mediating innate immunity. However, molecular details regarding parkin-mediated immune response remain to be elucidated. Here, we identified mitochondrial TSPO-VDAC complex to genetically inte...
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