Article
Efficacy of tenofovir disoproxil fumarate in antiretroviral therapy-naive and -experienced patients coinfected with HIV-1 and hepatitis B virus.
The Journal of infectious diseases - 1 Apr 2004
Dore Gregory J, Cooper David A, Pozniak Anton L, DeJesus Edwin, Zhong Lijie, Miller Michael D, Lu Biao, Cheng Andrew K
Abstract excerpt
BACKGROUND: Coinfection with human immunodeficiency virus type 1 (HIV-1) increases the risk of hepatitis B virus (HBV)-associated progressive liver disease. Lamivudine has potent activity against both HIV-1 and HBV; however, lamivudine-resistance mutations in HBV frequently develop. METHODS: Substudies of the safety and efficacy of tenofovir disoproxil fumarate (tenofovir DF) for patients coinfected with HIV and...
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