Article
Tenofovir monotherapy is effective in hepatitis B patients with antiviral treatment failure to adefovir in the absence of adefovir-resistant mutations.
Journal of hepatology - 1 Mar 2008
Tan Jessica, Degertekin Bulent, Wong Stephen N, Husain Munira, Oberhelman Kelly, Lok Anna S F
Abstract excerpt
BACKGROUND/AIMS: We sought to identify mutations associated with treatment failure to adefovir (ADV) and to determine virologic response to tenofovir (TDF) alone and in combination with emtricitabine (FTC) in these patients. METHODS: Serum samples prior to and after the change in treatment to TDF...
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