Article
Independent phenotype of binuclear hepatocytes and cellular localization of UbD.
Experimental and molecular pathology - 1 Oct 2010
Oliva Joan, Bardag-Gorce Fawzia, French Barbara A, Li Jun, French Samuel W
Abstract excerpt
Mice fed DDC (0.1%) for 10 weeks, and then withdrawn from the drug for 1 month, retain the ability to form Mallory-Denk bodies (MDBs) when the drug is refed for 7 days. The number of liver cells that form MDBs increased and partially replaced normal liver cells, at the end of 7 days of refeeding DDC. The MDBs that formed were associated with increased expression of UbD (also called FAT10) in the Mallory-Denk body...
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