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Article

The genetic background modulates susceptibility to mouse liver Mallory-Denk body formation and liver injury.

Hepatology (Baltimore, Md.) - 1 Sept 2008

Hanada Shinichiro, Strnad Pavel, Brunt Elizabeth M, Omary M Bishr

Abstract excerpt

UNLABELLED: Mallory-Denk bodies (MDBs) are hepatocyte inclusions found in several liver diseases and consist primarily of keratins 8 and 18 (K8/K18) and ubiquitin that are cross-linked by transglutaminase-2. We hypothesized that genetic variables contribute to the extent of MDB formation, because...

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Source

Identifiers

PMID: 18697208
DOI: 10.1002/hep.22436

Genes

DDC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18697208-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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