Article
Mallory body formation is associated with epigenetic phenotypic change in hepatocytes in vivo.
Experimental and molecular pathology - 1 Oct 2007
Bardag-Gorce Fawzia, Dedes Jennifer, French Barbara A, Oliva Joan V, Li Jun, French Samuel W
Abstract excerpt
Microarrays were done on the livers of mice fed DDC for 10 weeks, withdrawn 1 month (DDC primed livers) and refed 6 days, and compared with mice fed the control diet. The expression of a large number of genes changed when DDC was fed or refed. A Venn diagram analysis identified 649 genes where gene expression was changed in the same direction. The epigenetic memory of the DDC primed liver involved an increase in...
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