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Article

Ferroptosis is governed by differential regulation of transcription in liver cancer

10 May 2019

Abstract excerpt

Ferroptosis is an outcome of metabolic disorders and closely linked to liver cancer. However, the mechanism underlying the fine regulation of ferroptosis in liver cancer remains unclear. Here, we have identified two categories of genes: ferroptosis up-regulated factors (FUF) and ferroptosis down-regulated factors (FDF), which stimulate and suppress ferroptosis by affecting the synthesis of GSH. Furthermore, FUF...

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PMID: 31108460
DOI: 10.1016/j.redox.2019.101211

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