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Article

Mallory body forming cells express the preneoplastic hepatocyte phenotype.

Experimental and molecular pathology - 1 Apr 2006

Nan Li, Bardag-Gorce Fawzia, Wu Yong, Li Jun, French Barbara A, French Samuel W

Abstract excerpt

The livers of mice fed diethyl 1,4-dihydro-2,4,6,-trimethyl-3,5-pyridinedicarboxylate (DDC) for 10 weeks formed Mallory bodies (MBs) in clusters of hepatocytes. Mice withdrawn from DDC for 9 months developed liver tumors. In the present study, the phenotype of the hepatocytes that formed MBs and tumors was characterized. Immunoperoxidase and immunofluorescent stains were done on the DDC-treated mouse livers, as...

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Source

Identifiers

PMID: 16413534
DOI: 10.1016/j.yexmp.2005.11.001

Genes

DDC
AFP
FAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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