Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Small ubiquitin‐related modifiers

22 Feb 2005

Abstract excerpt

Serum autoantibodies against components of nuclear dots (anti-NDs), namely PML and Sp100, are specifically detected in 20% to 30% of patients with primary biliary cirrhosis (PBC). Although anti-ND antibodies are nonpathogenic, the mechanisms that lead to this unique reactivity are critical to understanding the loss of immune tolerance in PBC. Importantly, Sp100 and PML are both covalently linked to small...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Liver Diseases and Immunity
Share to Macrophage Migration Inhibitory Factor
Share to Systemic Lupus Erythematosus Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15726652
DOI: 10.1002/hep.20619

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Small ubiquitin‐related modifiersPMID 15726652Read ↗

Evidence for covalent modification of the nuclear dot-associated proteins PML and Sp100 by PIC1/SUMO-1.Semantic proximity Read ↗

Two Nuclear Dot‐Associated Proteins, PML and SplOO, are Often Co‐Autoimmunogenic in Patients with Primary Biliary CirrhosisSemantic proximity Read ↗

Autoantibodies in Primary Biliary Cholangitis: From Classical Markers to Emerging TargetsSemantic proximity Read ↗

Clinical significance of autoantibodies in primary biliary cirrhosis.Semantic proximity Read ↗

The peculiar autoimmunity of primary biliary cirrhosisSemantic proximity Read ↗

Autoantibodies to the Nuclear Sp100 Protein in Primary Biliary Cirrhosis and Associated Diseases: Epitope Specificity and Immunoglobulin Class DistributionSemantic proximity Read ↗

Concurrent AMA-M2 positivity confers higher risks of occult cholestatic liver injury among anti-CENPB-positive patientsSemantic proximity Read ↗

Etiology of primary biliary cirrhosis: the search for the culprit.Semantic proximity Read ↗

The autoimmunity of primary biliary cirrhosis and the clonal selection theorySemantic proximity Read ↗

Risk factors and prediction of long-term outcome in primary biliary cirrhosis.Semantic proximity Read ↗

Primary biliary cirrhosis: Clinical and laboratory criteria for its diagnosis.Semantic proximity Read ↗

Anti-gp210 and anti-centromere antibodies are different risk factors for the progression of primary biliary cirrhosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.