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Article

Alteration in interactions between tumor-infiltrating lymphocytes and tumor cells in human melanomas after chemotherapy or immunotherapy.

Cancer immunology, immunotherapy : CII - 1 Jan 1991

Itoh K, Hayakawa K, Salmeron M A, Legha S S, Murray J L, Talpaz M, Balch C M, Parkinson D R, Lee K, Zukiwski A A

Abstract excerpt

Alteration in interactions between tumor-infiltrating lymphocytes (TILs) and tumor cells after chemotherapy or immunotherapy was studied in metastatic melanoma patients. Tumors were harvested from surgical specimens 17 days after the end of chemotherapy with cisplatin, vinblastine, and dacarbazine (CVD). Tumors of nonlymph-node metastases from two responders yielded neither TILs nor tumor cells, whereas those...

Topics

Antineoplastic Combined Chemotherapy Protocols
Cell Communication
Cytotoxicity, Immunologic
Humans
Immunotherapy
Interferon Type I
Interleukin-2
Lymphocytes, Tumor-Infiltrating
Melanoma
Neoplasm Metastasis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Recombinant Proteins

Tumor Cells, Cultured

Source

Open in PubMed Open full text

Identifiers

PMID: 2059968
DOI: 10.1007/BF01744943
PMCID: PMC11038021

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2059968-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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