Article
Frequency of cytotoxic T lymphocyte precursors (CTLp) interacting with autologous tumor via the T-cell receptor: limiting dilution analysis of specific CTLp in peripheral blood and tumor-invaded lymph nodes of melanoma patients.
International journal of cancer - 1 Aug 1994
Mazzocchi A, Belli F, Mascheroni L, Vegetti C, Parmiani G, Anichini A
Abstract excerpt
The frequencies of cytotoxic T-lymphocyte precursors (CTLp) that lyse autologous tumor by a T-cell receptor (TCR)-dependent mechanism (specific CTLp) were evaluated by limiting dilution analysis (LDA) using lymphocytes from peripheral blood (PBL) and from surgically resected, tumor-invaded lymph...
Topics
- Adult
- Aged
- Female
- Hematopoietic Stem Cells
- Humans
- Lymph Nodes
- Lymphatic Metastasis
- Lymphocyte Activation
- Lymphocyte Subsets
- Male
- Melanoma
- Middle Aged
- Phenotype
- Receptors, Antigen, T-Cell
- Sensitivity and Specificity