Article
Production and characterization of tumor infiltrating lymphocyte clones derived from B16-F10 murine melanoma.
The Journal of investigative dermatology - 1 Aug 1991
Maeda K, Lafreniere R, Jerry L M
Abstract excerpt
The adoptive transfer of tumor infiltrating lymphocytes (TIL) in conjunction with recombinant interleukin-2 (rIL-2) for the treatment of advanced cancer has recently been under intense investigation. Despite extensive research, the precise surface phenotype of TIL remains to be fully defined. To elucidate this unsolved problem, we established 11 TIL clones derived from rIL-2 expanded TIL obtained from B16-F10...
Topics
- Adenocarcinoma
- Animals
- Blotting, Western
- Cell Division
- Cell Survival
- Clone Cells
- Cytotoxicity, Immunologic
- Female
- Immunotherapy, Adoptive
- Interleukin-2
- Lymphocytes, Tumor-Infiltrating
