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Article

EGFR expression variance in paired colorectal cancer primary and metastatic tumors.

Cancer biology & therapy - 1 Sept 2010

Yarom Nirit, Marginean Celia, Moyana Terence, Gorn-Hondermann Ivan, Birnboim H Chaim, Marginean Horia, Auer Rebecca C, Vickers Michael, Asmis Timothy R, Maroun Jean, Jonker Derek

Abstract excerpt

BACKGROUND: Previous studies indicate that drugs targeting the Epidermal Growth Factor Receptor (EGFR) signaling pathways can induce objective responses, prolong time to progression and improve survival of patients with metastatic colorectal cancer (mCRC). EGFR expression in the primary tumour may not predict response to these agents and data is conflicting regarding the correlation of EGFR expression in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20595818
DOI: 10.4161/cbt.10.5.12610

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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