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Article

The prognostic values of EGFR expression and KRAS mutation in patients with synchronous or metachronous metastatic colorectal cancer.

BMC cancer - 13 Dec 2013

Huang Ching-Wen, Tsai Hsiang-Lin, Chen Yi-Ting, Huang Chun-Ming, Ma Cheng-Jen, Lu Chien-Yu, Kuo Chao-Hung, Wu Deng-Chyang, Chai Chee-Yin, Wang Jaw-Yuan

Abstract excerpt

BACKGROUND: The epidermal growth factor receptor (EGFR)/RAS/RAF/MEK/MAPK pathway is an important pathway in the carcinogenesis, invasion and metastasis of colorectal cancers (CRCs). We conducted a retrospective study to determine the prognostic values of EGFR expression and KRAS mutation in patients with metastatic CRC (mCRC) based on synchronous or metachronous status. METHODS: From October 2002 to March 2012,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24330663
DOI: 10.1186/1471-2407-13-599
PMCID: PMC3878756

Genes

EGFR
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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