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Article

A Comprehensive Review on the Role of Genetic Factors in Neuromyelitis Optica Spectrum Disorder.

Frontiers in immunology - 1 Jan 2021

Ghafouri-Fard Soudeh, Azimi Tahereh, Taheri Mohammad

Abstract excerpt

Neuromyelitis optica spectrum disorders (NMOSD) comprise a variety of disorders being described by optic neuritis and myelitis. This disorder is mostly observed in sporadic form, yet 3% of cases are familial NMO. Different series of familial NMO cases have been reported up to now, with some of them being associated with certain HLA haplotypes. Assessment of HLA allele and haplotypes has also revealed association...

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Identifiers

PMID: 34675927
DOI: 10.3389/fimmu.2021.737673
PMCID: PMC8524039

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