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Article

A myriad of miRNA variants in control and Huntington's disease brain regions detected by massively parallel sequencing.

Nucleic acids research - 1 Nov 2010

Martí Eulàlia, Pantano Lorena, Bañez-Coronel Mónica, Llorens Franc, Miñones-Moyano Elena, Porta Sílvia, Sumoy Lauro, Ferrer Isidre, Estivill Xavier

Abstract excerpt

Huntington disease (HD) is a neurodegenerative disorder that predominantly affects neurons of the forebrain. We have applied the Illumina massively parallel sequencing to deeply analyze the small RNA populations of two different forebrain areas, the frontal cortex (FC) and the striatum (ST) of healthy individuals and individuals with HD. More than 80% of the small-RNAs were annotated as microRNAs (miRNAs) in all...

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Identifiers

PMID: 20591823
DOI: 10.1093/nar/gkq575
PMCID: PMC2978354

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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