Article
Impaired expression of peroxisome proliferator-activated receptor gamma in ulcerative colitis.
Gastroenterology - 1 May 2003
Dubuquoy Laurent, Jansson Emmelie A, Deeb Samir, Rakotobe Sabine, Karoui Mehdi, Colombel Jean-Frédéric, Auwerx Johan, Pettersson Sven, Desreumaux Pierre
Abstract excerpt
BACKGROUND & AIMS: The peroxisome proliferator-activated receptor gamma (PPAR gamma) has been proposed as a key inhibitor of colitis through attenuation of nuclear factor kappa B (NF-kappa B) activity. In inflammatory bowel disease, activators of NF-kappa B, including the bacterial receptor toll-...
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