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Article

HFE gene polymorphisms and severity in Portuguese patients with multiple sclerosis.

European journal of neurology - 1 Apr 2011

Bettencourt A, Silva A M, Santos E, Gomes S, Mendonça D, Costa P P, Faustino P, Silva B M

Abstract excerpt

BACKGROUND: High iron concentrations have been reported in oligodendrocytes, myelin and macrophages in multiple sclerosis (MS) lesions. It has been proposed that HFE gene polymorphisms could have a role in MS. METHODS: The C282Y and H63D HFE variants frequencies were determined in 373 patients with MS and compared with a normal population. RESULTS: No significant association was found between HFE polymorphisms...

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Share to Hemochromatosis Protein
Share to Histocompatibility Antigens Class I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Membrane Proteins

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Share to Polymorphism, Restriction Fragment Length

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Source

Identifiers

PMID: 20586792
DOI: 10.1111/j.1468-1331.2010.03109.x

Genes

HFE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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