Infection with specific Helicobacter pylori-cag pathogenicity island strains is associated with interleukin-1B gene polymorphisms in Venezuelan chronic gastritis patients.

doi:10.1007/s10620-010-1316-0

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Infection with specific Helicobacter pylori-cag pathogenicity island strains is associated with interleukin-1B gene polymorphisms in Venezuelan chronic gastritis patients.

Digestive diseases and sciences - 1 Feb 2011

Chiurillo Miguel Angel, Moran Yeinmy H, Cañas Miryan, Valderrama Elvis J, Armanie Emma

Abstract excerpt

BACKGROUND: The cag pathogenicity island (cag-PAI) is one of the major virulence factors of Helicobacter pylori, showing considerable geographic variation. AIM: We investigated the prevalence of cagA, cagE, and cagT genes of cag-PAI and their association with proinflammatory IL-1B-511/-31/+3954 polymorphisms in Venezuelan chronic gastritis patients from a high-risk gastric cancer region. METHODS: Presence of...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Antigens, Bacterial
Bacterial Proteins
Chronic Disease
Female
Gastritis
Genetic Predisposition to Disease
Helicobacter pylori

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Interleukin-1beta

Male

Middle Aged

Polymorphism, Genetic

Venezuela

Young Adult

Source

Open in PubMed

Identifiers

PMID: 20585978
DOI: 10.1007/s10620-010-1316-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-20585978-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Infection with specific Helicobacter pylori-cag pathogenicity island strains is associated with interleukin-1B gene polymorphisms in Venezuelan chronic gastritis patients.PMID 20585978Read ↗

Multiple cag genotypes of Helicobacter pylori isolates colonize the oesophagus in individual hosts in a Venezuelan population.Semantic proximity Read ↗

Combination of Helicobacter pylori-iceA2 and proinflammatory interleukin-1 polymorphisms is associated with the severity of histological changes in Venezuelan chronic gastritis patients.Semantic proximity Read ↗

Variations in Helicobacter pylori cytotoxin-associated genes and their influence in progression to gastric cancer: implications for prevention.Semantic proximity Read ↗

The importance of Helicobacter pylori tnpA, tnpB, and cagA genes in various gastrointestinal diseasesSemantic proximity Read ↗

Epidemiology of Helicobacter pylori and CagA-Positive Infections and Global Variations in Gastric CancerSemantic proximity Read ↗

Genotyping of Helicobacter pylori virulence-associated genes shows high diversity of strains infecting patients in western Venezuela.Semantic proximity Read ↗

Geographic differences and the role of cagA gene in gastroduodenal diseases associated with Helicobacter pylori infection.Semantic proximity Read ↗

Genotyping of Helicobacter pylori Virulence Genes cagA and vacA: Regional and National StudySemantic proximity Read ↗

Determination of Helicobacter pylori virulence by analysis of the cag pathogenicity island isolated from Iranian patients.Semantic proximity Read ↗

Helicobacter pylori cagA Promoter Region Sequences Influence CagA Expression and Interleukin 8 Secretion.Semantic proximity Read ↗

Variations in cag pathogenicity island genes of Helicobacter pylori from Latin American groups may influence neoplastic progression to gastric cancer.Semantic proximity Read ↗

Heterogeneity of cag genotypes of Helicobacter pylori in the esophageal mucosa of dyspeptic patients and its relation to histopathological outcomes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.