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Article

Variations in cag pathogenicity island genes of Helicobacter pylori from Latin American groups may influence neoplastic progression to gastric cancer.

Scientific reports - 16 Apr 2020

Rizzato Cosmeri, Torres Javier, Obazee Ofure, Camorlinga-Ponce Margarita, Trujillo Esperanza, Stein Angelika, Mendez-Tenorio Alfonso, Bravo Maria Mercedes, Canzian Federico, Kato Ikuko

Abstract excerpt

Helicobacter pylori (HP) colonizes the human stomach and induces acute gastritis, peptic ulcer disease, atrophic gastritis, and gastric adenocarcinoma. Increased virulence in HP isolates derives from harboring the cag (cytotoxin-associated genes) pathogenicity island (cagPAI). We analyzed the microvariants in cagPAI genes with the hypothesis that they may play an important role in determining HP virulence. We...

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Identifiers

PMID: 32300197
DOI: 10.1038/s41598-020-63463-0
PMCID: PMC7162905

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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