Article
Combination of Helicobacter pylori-iceA2 and proinflammatory interleukin-1 polymorphisms is associated with the severity of histological changes in Venezuelan chronic gastritis patients.
FEMS immunology and medical microbiology - 1 Jul 2010
Chiurillo Miguel Angel, Moran Yeinmy, Cañas Miryan, Valderrama Elvis, Alvarez Alberto, Armanie Emma
Abstract excerpt
Helicobacter pylori is a major cause of chronic gastritis (CG) and a firmly established carcinogen for gastric adenocarcinoma. However, the underlying pathogenic mechanisms are not fully understood. In this work we studied the association of the allelic variation of H. pylori-iceA virulence factor and human proinflammatory interleukin (IL)-1 polymorphisms (IL-1B-31, IL-1B-511, IL-1B+3954 and IL-1RN) with...
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