Article
Heterogeneity of cag genotypes of Helicobacter pylori in the esophageal mucosa of dyspeptic patients and its relation to histopathological outcomes.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Sept 2014
Contreras Monica, Abrante Ligia, Salazar Víctor, Reyes Nelson, García-Amado María Alexandra, Fernández-Delgado Milagro, Romero Roberto, Rojas Héctor, Michelangeli Fabian
Abstract excerpt
BACKGROUND: A high prevalence of Helicobacter pylori in the esophageal mucosa of dyspeptic Venezuelan patients has been reported. We aimed to assess the genetic composition of the cag genotypes of H. pylori and its relation to histopathological outcomes in the gastroesophageal mucosa. METHODS: The presence of cagA, cagE, and virB11 cag pathogenicity island (PAI) genes was detected by PCR in 80 of 150 H....
Topics
- Adult
- Aged
- Antigens, Bacterial
- Bacterial Proteins
- Dyspepsia
- Esophagus
- Female
- Genomic Islands
- Genotype
- Helicobacter Infections
- Helicobacter pylori
- Humans