Article
Genotyping of Helicobacter pylori virulence-associated genes shows high diversity of strains infecting patients in western Venezuela.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Sept 2013
Chiurillo Miguel Angel, Moran Yeinmy, Cañas Miryan, Valderrama Elvis, Granda Nashdalish, Sayegh Marjorie, Ramírez José Luis
Abstract excerpt
BACKGROUND: Helicobacter pylori is a major cause of chronic gastritis and an established risk factor for gastric adenocarcinoma. This bacterium also exhibits an extraordinarily high genetic diversity. METHODS: The genetic diversity of H. pylori strains from Venezuelan patients with chronic gastritis was evaluated by PCR-typing of vacA, cagA, iceA, and babA2 virulence-associated genes using DNA extracted directly...
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