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Article

Ascorbate peroxidase from Leishmania major controls the virulence of infective stage of promastigotes by regulating oxidative stress.

PloS one - 23 Jun 2010

Pal Swati, Dolai Subhankar, Yadav Rajesh K, Adak Subrata

Abstract excerpt

BACKGROUND: Peroxidase represents a heterogeneous group of distinct enzyme family that plays extremely diverse biological functions. Ascorbate peroxidase from Leishmania major (LmAPX) has been shown to be central to the redox defense system of Leishmania. To investigate further its exact physiological role in Leishmania, we attempted to create LmAPX -knockout mutants by gene replacement in L. major strains....

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Identifiers

PMID: 20585663
DOI: 10.1371/journal.pone.0011271
PMCID: PMC2890587

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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