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Article

The Dangerous Liaisons in the Oxidative Stress Response to Leishmania Infection

28 Mar 2022

Abstract excerpt

Leishmania parasites preferentially invade macrophages, the professional phagocytic cells, at the site of infection. Macrophages play conflicting roles in Leishmania infection either by the destruction of internalized parasites or by providing a safe shelter for parasite replication. In response to invading pathogens, however, macrophages induce an oxidative burst as a mechanism of defense to promote pathogen...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35456085
DOI: 10.3390/pathogens11040409

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