Article
Cryptococcus neoformans histone acetyltransferase Gcn5 regulates fungal adaptation to the host.
Eukaryotic cell - 1 Aug 2010
O'Meara Teresa R, Hay Christie, Price Michael S, Giles Steve, Alspaugh J Andrew
Abstract excerpt
Cryptococcus neoformans is an environmental fungus and an opportunistic human pathogen. Previous studies have demonstrated major alterations in its transcriptional profile as this microorganism enters the hostile environment of the human host. To assess the role of chromatin remodeling in host-induced transcriptional responses, we identified the C. neoformans Gcn5 histone acetyltransferase and demonstrated its...
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