Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Geographic distribution of rare variants associated with age-related macular degeneration.

Molecular vision - 1 Jan 2018

Geerlings Maartje J, Kersten Eveline, Groenewoud Joannes M M, Fritsche Lars G, Hoyng Carel B, de Jong Eiko K, den Hollander Anneke I

Abstract excerpt

Purpose: A recent genome-wide association study by the International Age-related Macular Degeneration Genomics Consortium (IAMDGC) identified seven rare variants that are individually associated with age-related macular degeneration (AMD), the most common cause of vision loss in the elderly. In literature, several of these rare variants have been reported with different frequencies and odds ratios across...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Complement C3
Share to Complement Factor H

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Complement Factor I

Share to Europe

Share to Gene Expression

Share to Genome-Wide Association Study

Share to Geography

Share to Macular Degeneration

Source

Open in PubMed Open full text

Identifiers

PMID: 29410599
PMCID: PMC5788811

Genes

CFH
CFI

Variants

rs121913059
rs141853578
rs147859257
rs34882957

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Geographic distribution of rare variants associated with age-related macular degeneration.PMID 29410599Read ↗

Rare Genetic Variants Associated With Development of Age-Related Macular Degeneration.Semantic proximity Read ↗

The Effect of Genetic Variants Associated With Age-Related Macular Degeneration Varies With Age.Semantic proximity Read ↗

Highly penetrant alleles in age-related macular degeneration.Semantic proximity Read ↗

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants.Semantic proximity Read ↗

Identification of a rare coding variant in complement 3 associated with age-related macular degeneration.Semantic proximity Read ↗

Rare Variants in the Functional Domains of Complement Factor H Are Associated With Age-Related Macular Degeneration.Semantic proximity Read ↗

Age-related macular degeneration-susceptibility single nucleotide polymorphisms in a han chinese control population.Semantic proximity Read ↗

Whole Genome Sequencing Identifies Novel Common and Low-Frequency Variants Associated With Age-Related Macular Degeneration.Semantic proximity Read ↗

Investigating the CFH Gene Polymorphisms as a Risk Factor for Age-related Macular Degeneration in an Iranian Population.Semantic proximity Read ↗

Comparison of risk allele frequencies of single nucleotide polymorphisms associated with age-related macular degeneration in different ethnic groups.Semantic proximity Read ↗

Phenotype Characteristics of Patients With Age-Related Macular Degeneration Carrying a Rare Variant in the Complement Factor H Gene.Semantic proximity Read ↗

Rare predicted loss-of-function and damaging missense variants in CFHR5 associate with protection from age-related macular degeneration.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.