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Article

The Effect of Genetic Variants Associated With Age-Related Macular Degeneration Varies With Age.

Investigative ophthalmology & visual science - 1 Dec 2020

Schick Tina, Lorés-Motta Laura, Altay Lebriz, Fritsche Lars G, den Hollander Anneke I, Fauser Sascha

Abstract excerpt

Purpose: The prevalence of age-related macular degeneration (AMD) increases dramatically with age. This large collaborative study investigates the effects of 51 late-AMD-associated genetic variants in different ages, focusing on individuals above the age of 90 years. Methods: The study included 27,996 individuals of the International AMD Genomics Consortium; 14,539 showed late AMD (51.9%) and 13,457 were controls...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33320170
DOI: 10.1167/iovs.61.14.17
PMCID: PMC7745630

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