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Article

The early nutritional environment of mice determines the capacity for adipose tissue expansion by modulating genes of caveolae structure.

PloS one - 21 Jun 2010

Kozak Leslie P, Newman Susan, Chao Pei-Min, Mendoza Tamra, Koza Robert A

Abstract excerpt

While the phenomenon linking the early nutritional environment to disease susceptibility exists in many mammalian species, the underlying mechanisms are unknown. We hypothesized that nutritional programming is a variable quantitative state of gene expression, fixed by the state of energy balance in the neonate, that waxes and wanes in the adult animal in response to changes in energy balance. We tested this...

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Identifiers

PMID: 20574519
DOI: 10.1371/journal.pone.0011015
PMCID: PMC2888576

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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