Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Maternal high-fat diet programs white and brown adipose tissue lipidome and transcriptome in offspring in a sex- and tissue-dependent manner in mice

7 Jan 2022

Abstract excerpt

OBJECTIVE: The prevalence of overweight and obesity among children has drastically increased during the last decades and maternal obesity has been demonstrated as one of the ultimate factors. Nutrition-stimulated transgenerational regulation of key metabolic genes is fundamental to the developmental origins of the metabolic syndrome. Fetal nutrition may differently influence female and male offspring. METHODS:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue and Metabolism
Share to Birth, Development, and Health
Share to Regulation of Appetite and Obesity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34997206
DOI: 10.1038/s41366-021-01060-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Maternal high-fat diet programs white and brown adipose tissue lipidome and transcriptome in offspring in a sex- and tissue-dependent manner in micePMID 34997206Read ↗

Maternal obesity programs white and brown adipose tissue transcriptome and lipidome in offspring in a sex-dependent mannerSemantic proximity Read ↗

Maternal high-fat diet induces long-term obesity with sex-dependent metabolic programming of adipocyte differentiation, hypertrophy and dysfunction in the offspringSemantic proximity Read ↗

Molecular programming modulates hepatic lipid metabolism and adult metabolic risk in the offspring of obese mothers in a sex-specific mannerSemantic proximity Read ↗

Developmental programming of offspring adipose tissue biology and obesity riskSemantic proximity Read ↗

Transcriptomic responses are sex-dependent in the skeletal muscle and liver in offspring of obese miceSemantic proximity Read ↗

Maternal Western-Style High Fat Diet Induces Sex-Specific Physiological and Molecular Changes in Two-Week-Old Mouse OffspringSemantic proximity Read ↗

Obese mother offspring have hepatic lipidic modulation that contributes to sex-dependent metabolic adaptation later in lifeSemantic proximity Read ↗

Metabolomic and transcriptomic remodeling of bone marrow myeloid cells in response to maternal obesitySemantic proximity Read ↗

Sex-Dependent Epigenomic and Transcriptomic Reprogramming Links Maternal Obesity to Cardiac Remodeling in Adult OffspringSemantic proximity Read ↗

Genetic, metabolic, and molecular insights into the diverse outcomes of diet-induced obesity in miceSemantic proximity Read ↗

Sexual Dimorphism in Offspring Glucose-Sensitive Hypothalamic Gene Expression and Physiological Responses to Maternal High-Fat Diet FeedingSemantic proximity Read ↗

Gene expression in normal-weight mice offspring from parents on Western Diets suggests altered risk for obesity and metabolic diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.