Article
Role of complement factor H I62V and age-related maculopathy susceptibility 2 A69S variants in the clinical expression of polypoidal choroidal vasculopathy.
Ophthalmology - 1 Jul 2011
Sakurada Yoichi, Kubota Takeo, Imasawa Mitsuhiro, Mabuchi Fumihiko, Tateno Yasushi, Tanabe Naohiko, Iijima Hiroyuki
Abstract excerpt
PURPOSE: To investigate the role of complement factor H (CFH) I62V (rs800292) and age-related maculopathy susceptibility 2 (ARMS2) A69S (rs10490924) variants in the clinical characteristics of polypoidal choroidal vasculopathy (PCV). DESIGN: Cross-sectional study. PARTICIPANTS: A total of 226 Japanese patients with PCV in both eyes (44 cases) or in 1 eye (182 cases). METHODS: Genotyping was performed in all cases...
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