Article
Effect of trimethoprim-sulphamethoxazole on the risk of malaria in HIV-infected Ugandan children living in an area of widespread antifolate resistance.
Malaria journal - 23 Jun 2010
Gasasira Anne F, Kamya Moses R, Ochong Edwin O, Vora Neil, Achan Jane, Charlebois Edwin, Ruel Theodore, Kateera Fredrick, Meya Denise N, Havlir Diane, Rosenthal Philip J, Dorsey Grant
Abstract excerpt
BACKGROUND: Daily trimethoprim-sulfamethoxazole (TS) protects against malaria, but efficacy may be diminished as anti-folate resistance increases. This study assessed the incidence of falciparum malaria and the prevalence of resistance-conferring Plasmodium falciparum mutations in HIV-infected children receiving daily TS and HIV-uninfected children not taking TS. MATERIALS AND METHODS: Subjects were 292...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.