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Article

Breast carcinoma-associated fibroblasts rarely contain p53 mutations or chromosomal aberrations.

Cancer research - 15 Jul 2010

Hosein Abdel Nasser, Wu Min, Arcand Suzanna L, Lavallée Sylvie, Hébert Josée, Tonin Patricia N, Basik Mark

Abstract excerpt

It has become increasingly clear that the cells within the tumor microenvironment play a critical role in cancer growth and metastasis. Studies in experimental models suggest that carcinoma-associated fibroblasts (CAF) differ from normal fibroblasts and are capable of promoting cancer progression through a variety of mechanisms. At present, a definitive view is lacking on whether genomic abnormalities are present...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20570891
DOI: 10.1158/0008-5472.CAN-10-0673

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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