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Article

Highly variable response to cytotoxic chemotherapy in carcinoma-associated fibroblasts (CAFs) from lung and breast.

BMC cancer - 11 Dec 2008

Sonnenberg Maike, van der Kuip Heiko, Haubeis Silke, Fritz Peter, Schroth Werner, Friedel Godehard, Simon Wolfgang, Mürdter Thomas E, Aulitzky Walter E

Abstract excerpt

BACKGROUND: Carcinoma-associated fibroblasts (CAFs) can promote carcinogenesis and tumor progression. Only limited data on the response of CAFs to chemotherapy and their potential impact on therapy outcome are available. This study was undertaken to analyze the influence of chemotherapy on carcin...

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Identifiers

PMID: 19077243
DOI: 10.1186/1471-2407-8-364
PMCID: PMC2626600

Genes

ERCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19077243-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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