Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The impact of cross-immunity, mutation and stochastic extinction on pathogen diversity.

Proceedings. Biological sciences - 7 Dec 2004

Abu-Raddad Laith J, Ferguson Neil M

Abstract excerpt

We examine the dynamics of antigenically diverse infectious agents using a mathematical model describing the transmission dynamics of arbitrary numbers of pathogen strains, interacting via cross-immunity, and in the presence of mutations generating new strains and stochastic extinctions of existing ones. Equilibrium dynamics fall into three classes depending on cross-immunity, transmissibility and host population...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigenic Variation
Share to Biodiversity
Share to Biological Evolution

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Communicable Diseases

Share to Cross Reactions

Share to Population Density

Share to Population Dynamics

Share to Stochastic Processes

Source

Open in PubMed Open full text

Identifiers

PMID: 15590592
DOI: 10.1098/rspb.2004.2877
PMCID: PMC1691886

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The impact of cross-immunity, mutation and stochastic extinction on pathogen diversity.PMID 15590592Read ↗

Incorporating demographic stochasticity into multi-strain epidemic models: application to influenza A.Semantic proximity Read ↗

Improving the realism of deterministic multi-strain models: implications for modelling influenza A.Semantic proximity Read ↗

Antigenic diversity, transmission mechanisms, and the evolution of pathogens.Semantic proximity Read ↗

Host immunity and pathogen diversity: A computational study.Semantic proximity Read ↗

Increased frequency of travel in the presence of cross-immunity may act to decrease the chance of a global pandemicSemantic proximity Read ↗

Integrating life history and cross-immunity into the evolutionary dynamics of pathogensSemantic proximity Read ↗

Enriched pathogen diversity under host-type heterogeneity and immune-mediated competitionSemantic proximity Read ↗

The reinfection threshold regulates pathogen diversity: the case of influenza.Semantic proximity Read ↗

Characterization of the endemic equilibrium and response to mutant injection in a multi-strain disease model.Semantic proximity Read ↗

Multi-strain disease dynamics on metapopulation networksSemantic proximity Read ↗

Cross-scale dynamics and the evolutionary emergence of infectious diseasesSemantic proximity Read ↗

A limited host immune range facilitates the creation and maintenance of diversity in parasite virulenceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.