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Article

Prion protein expression and the M129V polymorphism of the PRNP gene in patients with colorectal cancer.

Molecular carcinogenesis - 1 Jul 2010

Antonacopoulou Anna G, Palli Maria, Marousi Stella, Dimitrakopoulos Fotinos-Ioannis, Kyriakopoulou Urania, Tsamandas Athanasios C, Scopa Chrisoula D, Papavassiliou Athanasios G, Kalofonos Haralabos P

Abstract excerpt

The prion protein, PrP(C), is known mostly for its involvement in neurodegenerative spongiform encephalopathies. However, a role for this molecule in cancer is becoming increasingly recognized partly because it promotes cell proliferation and inhibits apoptosis. Moreover, the codon 129 polymorphi...

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Source

Identifiers

PMID: 20564346
DOI: 10.1002/mc.20642

Genes

PRNP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20564346-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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