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Article

Codon 129 polymorphism of prion protein gene in sporadic Alzheimer's disease.

European journal of neurology - 1 Feb 2008

Poleggi A, Bizzarro A, Acciarri A, Antuono P, Bagnoli S, Cellini E, Forno G Dal, Giannattasio C, Lauria A, Matera M G, Nacmias B, Puopolo M, Seripa D, Sorbi S, Wekstein D R, Pocchiari M, Masullo C

Abstract excerpt

Codon 129 polymorphism of the prion protein gene represents a major genetic risk factor for Creutzfeldt-Jakob disease (CJD). Both CJD and Alzheimer's disease (AD) are brain amyloidoses and it would be possible that codon 129 polymorphism plays a role in the susceptibility to AD. In order to investigate this polymorphism in AD the distribution of polymorphic codon 129 of the PRNP gene in 194 probable AD and 124...

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Source

Identifiers

PMID: 18217885
DOI: 10.1111/j.1468-1331.2007.02021.x

Genes

PRNP
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Codon 129 polymorphism of prion protein gene in sporadic Alzheimer's disease.PMID 18217885Read ↗

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Prion protein codon 129 genotype prevalence is altered in primary progressive aphasia.Semantic proximity Read ↗

Polymorphisms of the prion protein gene in Italian patients with Creutzfeldt-Jakob disease.Semantic proximity Read ↗

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