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Article

The M129V polymorphism of codon 129 in the prion gene (PRNP) in the Danish population.

European journal of epidemiology - 1 Jan 2008

Dyrbye Henrik, Broholm Helle, Dziegiel Morten Hanefeld, Laursen Henning

Abstract excerpt

Since variant Creutzfeldt-Jakob disease (vCJD) was described for the first time in 1995 and fears of an epidemic ensued, the assumed culprit the prion protein (PrP) and its precursor the prion-gene (PRNP) have been subjects to intense studies. Several polymorphisms in PRNP modify disease probability and phenotype. Importantly, two common variants of codon 129 in PRNP code for methionine (Met) or valine (Val),...

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Identifiers

PMID: 17987393
DOI: 10.1007/s10654-007-9197-z

Genes

PRNP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The M129V polymorphism of codon 129 in the prion gene (PRNP) in the Danish population.PMID 17987393Read ↗

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PRNP variation in UK sporadic and variant Creutzfeldt Jakob disease highlights genetic risk factors and a novel non-synonymous polymorphism.Semantic proximity Read ↗

Significant association of a M129V independent polymorphism in the 5′ UTR of the <i>PRNP</i> gene with sporadic Creutzfeldt-Jakob disease in a large German case-control studySemantic proximity Read ↗

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