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Article

Insights into colon cancer etiology via a regularized approach to gene set analysis of GWAS data.

American journal of human genetics - 11 Jun 2010

Chen Lin S, Hutter Carolyn M, Potter John D, Liu Yan, Prentice Ross L, Peters Ulrike, Hsu Li

Abstract excerpt

Genome-wide association studies (GWAS) have successfully identified susceptibility loci from marginal association analysis of SNPs. Valuable insight into genetic variation underlying complex diseases will likely be gained by considering functionally related sets of genes simultaneously. One approach is to further develop gene set enrichment analysis methods, which are initiated in gene expression studies, to...

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Identifiers

PMID: 20560206
DOI: 10.1016/j.ajhg.2010.04.014
PMCID: PMC3032068

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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