Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ATM and ATR homologes of Neurospora crassa are essential for normal cell growth and maintenance of chromosome integrity.

Fungal genetics and biology : FG & B - 1 Oct 2010

Wakabayashi Michiyoshi, Ishii Chizu, Hatakeyama Shin, Inoue Hirokazu, Tanaka Shuuitsu

Abstract excerpt

Genome integrity is maintained by many cellular mechanisms in eukaryotes. One such mechanism functions during the cell cycle and is known as the DNA damage checkpoint. In the filamentous fungus Neurospora crassa, mus-9 and mus-21 are homologes of two key factors of the mammalian DNA damage checkpoint, ATR and ATM, respectively. We previously showed that mus-9 and mus-21 mutants are sensitive to DNA damage and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ataxia Telangiectasia Mutated Proteins
Share to Cell Cycle Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Fungal

Share to Fungal Proteins

Share to Neurospora crassa

Share to Protein Serine-Threonine Kinases

Share to Sequence Alignment

Share to Tumor Suppressor Proteins

Source

Identifiers

PMID: 20553930
DOI: 10.1016/j.fgb.2010.05.010

Genes

ATM
ATR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ATM and ATR homologes of Neurospora crassa are essential for normal cell growth and maintenance of chromosome integrity.PMID 20553930Read ↗

Neurospora mrc1 homologue is involved in replication stability and is required for normal cell growth and chromosome integrity in mus-9 and mus-21 mutants.Semantic proximity Read ↗

Genetic analysis of CHK1 and CHK2 homologues revealed a unique cross talk between ATM and ATR pathways in Neurospora crassa.Semantic proximity Read ↗

Genetic and molecular characterization of Neurospora crassa mus-23: a gene involved in recombinational repair.Semantic proximity Read ↗

Abnormal chromosome behavior in Neurospora mutants defective in DNA methylation.Semantic proximity Read ↗

Aspergillus nidulans as a model system to characterize the DNA damage response in eukaryotes.Semantic proximity Read ↗

Different roles of the Mre11 complex in the DNA damage response in Aspergillus nidulans.Semantic proximity Read ↗

Genetic analysis of the Neurospora crassa RAD14 homolog mus-43 and the RAD10 homolog mus-44 reveals that they belong to the mus-38 pathway of two nucleotide excision repair systems.Semantic proximity Read ↗

Exploring the processes of DNA repair and homologous integration in Neurospora.Semantic proximity Read ↗

The Saccharomyces cerevisiae checkpoint genes RAD9, CHK1 and PDS1 are required for elevated homologous recombination in a mec1 (ATR) hypomorphic mutant.Semantic proximity Read ↗

mus-52 disruption and metabolic regulation in Neurospora crassa: Transcriptional responses to extracellular phosphate availability.Semantic proximity Read ↗

A new UV-sensitive mutant that suggests a second excision repair pathway in Neurospora crassa.Semantic proximity Read ↗

Highly efficient gene replacements in Neurospora strains deficient for nonhomologous end-joining.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.