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Article

Genetic analysis of CHK1 and CHK2 homologues revealed a unique cross talk between ATM and ATR pathways in Neurospora crassa.

DNA repair - 1 Dec 2008

Wakabayashi Michiyoshi, Ishii Chizu, Inoue Hirokazu, Tanaka Shuuitsu

Abstract excerpt

DNA damage checkpoint is an important mechanism for organisms to maintain genome integrity. In Neurospora crassa, mus-9 and mus-21 are homologues of ATR and ATM, respectively, which are pivotal factors of DNA damage checkpoint in mammals. A N. crassa clock gene prd-4 has been identified as a CHK2 homologue, but its role in DNA damage response had not been elucidated. In this study, we identified another CHK2...

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Source

Identifiers

PMID: 18790091
DOI: 10.1016/j.dnarep.2008.08.004

Genes

ATM
ATR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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