Article
mus-52 disruption and metabolic regulation in Neurospora crassa: Transcriptional responses to extracellular phosphate availability.
PloS one - 1 Jan 2018
Martins Maíra P, Gomes Eriston V, Sanches Pablo R, Pedersoli Wellington R, Martinez-Rossi Nilce M, Rossi Antonio
Abstract excerpt
Advances in the understanding of molecular systems depend on specific tools like the disruption of genes to produce strains with the desired characteristics. The disruption of any mutagen sensitive (mus) genes in the model fungus Neurospora crassa, i.e. mus-51, mus-52, or mus-53, orthologous to the human genes KU70, KU80, and LIG4, respectively, provides efficient tools for gene targeting. Accordingly, we used...
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