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Article

Haptoglobin and sickle cell polymorphisms and risk of active trachoma in Gambian children.

PloS one - 11 Jun 2010

Savy Mathilde, Hennig Branwen J, Doherty Conor P, Fulford Anthony J, Bailey Robin, Holland Martin J, Sirugo Giorgio, Rockett Kirk A, Kwiatkowski Dominic P, Prentice Andrew M, Cox Sharon E

Abstract excerpt

BACKGROUND: Susceptibility and resistance to trachoma, the leading infectious cause of blindness, have been associated with a range of host genetic factors. In vitro studies of the causative organism, Chlamydia trachomatis, demonstrate that iron availability regulates its growth, suggesting that host genes involved in regulating iron status and/or availability may modulate the risk of trachoma. The objective was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20552021
DOI: 10.1371/journal.pone.0011075
PMCID: PMC2884021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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