Article
Sequence based HLA-DRB1, -DQB1 and -DPB1 allele and haplotype frequencies in The Gambia.
Human immunology - 1 Feb 2023
Barton Amber, Pickering Harry, Payne Thomas, Faal Nkoyo, Sillah Ansumana, Harte Anna, Bailey Robin L, Mabey David C W, Roberts Chrissy H, Holland Martin J
Abstract excerpt
Class II HLA loci DRB1, DQB1 and DPB1 were typed for a total of 939 Gambian participants by locus-specific amplicon sequencing. Participants were from multiple regions of The Gambia and drawn from two studies: a family study aiming to identify associations between host genotype and trachomatous scarring (N = 796) and a cohort study aiming to identify correlates of immunity to trachoma (N = 143). All loci deviated...
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