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Article

Association between genetic variants in the 8q24 cancer risk regions and circulating levels of androgens and sex hormone-binding globulin.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jul 2010

Chu Lisa W, Meyer Tamra E, Li Qizhai, Menashe Idan, Yu Kai, Rosenberg Philip S, Huang Wen-Yi, Quraishi Sabah M, Kaaks Rudolf, Weiss Jocelyn M, Hayes Richard B, Chanock Stephen J, Hsing Ann W

Abstract excerpt

BACKGROUND: Genome-wide association studies have identified multiple independent regions on chromosome 8q24 that are associated with cancers of the prostate, breast, colon, and bladder. METHODS: To investigate their biological basis, we examined the possible association between 164 single nucleotide polymorphisms (SNPs) in the 8q24 risk regions spanning 128,101,433-128,828,043 bp, and serum androgen...

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Identifiers

PMID: 20551303
DOI: 10.1158/1055-9965.EPI-10-0101
PMCID: PMC2901401

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Source receipt: pubmed, retrieved 7 Sept 2026.

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