Article
Functional variants of Fc gamma receptor (FCGR2A) and FCGR3A are not associated with susceptibility to systemic sclerosis in a large European Study (EUSTAR).
The Journal of rheumatology - 1 Aug 2010
Alizadeh Behrooz Z, Broen Jasper, Rueda Blanca, Hesselstrand Roger, Wuttge Dirk, Simeon Carmen, Ortego-Centeno Norberto, Gonzalez-Gay Miguel A, Gonzalez-Gay Miguel, Pros Anna, Herrick Ariane, Worthington Jane, Denton Christopher, Fonseca Carmen, Riemekasten Gabriela, Vonk Madelon C, van den Hoogen Frank, Guiducci Serena, Matucci-Cerinic Marco, Scorza Rafaella, Beretta Lorenzo, Airó Paolo, Coenen Marieke, Martin Javier, Koeleman Bobby P C, Radstake Timothy R D J
Abstract excerpt
OBJECTIVE: To investigate the possible role of FCGR2A 519A>G and FCGR3A 559A>C functional polymorphisms in the genetic predisposition to susceptibility to systemic sclerosis (SSc) or clinical phenotype. METHODS: A total of 1566 patients with SSc and 2271 geographically matched controls were included in our study. We analyzed the genotype and allele frequencies of the FCGR2A 519A>G and FCGR3A 559A>C functional...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.