A candidate gene study reveals association between a variant of the SRp55 splicing factor gene and systemic sclerosis.

doi:10.55563/clinexprheumatol/mpgq0y

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Article

A candidate gene study reveals association between a variant of the SRp55 splicing factor gene and systemic sclerosis.

Clinical and experimental rheumatology - 1 Oct 2022

Romano Eloisa, Rosa Irene, Fioretto Bianca Saveria, Kosalka-Wegiel Joanna, Sticchi Elena, Bellando-Randone Silvia, Manetti Mirko, Matucci-Cerinic Marco

Abstract excerpt

OBJECTIVES: To examine the possible implication of the mRNA-binding protein serine/arginine protein 55 (SRp55, also known as SRSF6) rs2235611 single nucleotide polymorphism (SNP) in the genetic predisposition to systemic sclerosis (SSc) susceptibility and clinical phenotype. METHODS: A total population of 872 white Italian individuals (414 SSc patients, 458 controls) was studied. SSc patients were assessed for...

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PMID: 34665708
DOI: 10.55563/clinexprheumatol/mpgq0y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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