Article
BCRgt: a Bayesian cluster regression-based genotyping algorithm for the samples with copy number alterations.
BMC bioinformatics - 15 Mar 2014
Yang Shengping, Cui Xiangqin, Fang Zhide
Abstract excerpt
BACKGROUND: Accurate genotype calling is a pre-requisite of a successful Genome-Wide Association Study (GWAS). Although most genotyping algorithms can achieve an accuracy rate greater than 99% for genotyping DNA samples without copy number alterations (CNAs), almost all of these algorithms are not designed for genotyping tumor samples that are known to have large regions of CNAs. RESULTS: This study aims to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
